Plasma Exchange in the Management of Catastrophic Antiphospholipid Syndrome

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Plasma Exchange in the Management of Catastrophic Antiphospholipid Syndrome

Objective. Report of a case of catastrophic antiphospholipid syndrome (CAPS) with multiple organ involvement leading to a life-threatening condition despite early combination corticosteroid and heparin therapy. Initiation of plasma exchange led to rapid improvement of the patient's general condition. Design. CASE REPORT Setting. University teaching hospital medical intensive care unit. Patien...

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Current management of catastrophic antiphospholipid syndrome

The catastrophic variant of the antiphospholipid syndrome (APS) is the most severe form and is characterized by clinical evidence of multiple organ involvement developing over a short period of time, histopathological evidence of small vessel occlusions and laboratory confirmation of antiphospholipid antibodies (aPL) as assessed in 2003 in the international consensus statement on the classifica...

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[Catastrophic antiphospholipid syndrome: CAPS].

Antiphospholipid syndrome (APS) is well known as an autoimmune thrombotic syndrome with recurrent thromboses. In APS, thromboses occurs both artery and vein, and from large to micro vessels. In contrast, so called catastrophic antiphospholipid syndrome, CAPS, develops multiple thromboses at microvessels mainly within a few weeks and induces to poor prognosis. CAPS often occurs in patients with ...

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Catastrophic Primary Antiphospholipid Syndrome

drome (APLS) may present with a catastrophic condition characterized by multiple vascular occlusions that often result in death if appropriate treatment is not quickly applied. In the great majority of cases, patients with catastrophic APLS show a spontaneous tendency to develop microvascular thrombosis that affects multiple organs. However, arterial reactivity leading to acute thrombosis after...

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Catastrophic antiphospholipid syndrome (CAPS).

Catastrophic antiphospholipid syndrome (CAPS) is a very severe variant of the classic APS, characterised by clinical evidence of multiple organ involvement developing over a very short period of time, histopathological evidence of multiple small vessel occlusions and laboratory confirmation of the presence of antiphospholipid antibodies (aPL), usually in high titre. Although patients with catas...

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ژورنال

عنوان ژورنال: Case Reports in Critical Care

سال: 2016

ISSN: 2090-6420,2090-6439

DOI: 10.1155/2016/5375080